Rett syndrome is a unique neurodevelopmental disorder that is first noticed in infancy and primarily affects girls, but can be rarely seen in boys. It is caused by mutations on the X-chromosome on a gene called MECP2. There are more than 200 different mutations found on the MECP2 gene. Most of these mutations are found in eight different “hot spots.”
DelveInsight’s “Rett Syndrome Market Insights, Epidemiology, and Market Forecast-2030″ report delivers an in-depth understanding of the Rett Syndrome , historical and forecasted epidemiology as well as the Rett Syndrome market trends in the United States, EU5 (Germany, Spain, Italy, France, and United Kingdom) and Japan.
Some of Rett Syndrome Facts:
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Rett syndrome is mostly misdiagnosed as autism, cerebral palsy, or global developmental delay. It is found in all ethnic and racial groups. Rett syndrome is not a degenerative disorder but causes problems in brain function that are responsible for cognitive, sensory, emotional, motor and autonomic function. These can include learning, speech, sensory sensations, mood, movement, breathing, cardiac function, and even chewing, swallowing, and digestion.
Symptoms of Rett syndrome appear after an early period of apparently normal or near normal development until six to eighteen months of life, when there is a slowing down or stagnation of skills.
Scientists generally describe four stages of Rett syndrome. Stage I, called early onset, typically begins between 6 and 18 months of age. Stage II, or the rapid destructive stage, usually begins between ages 1 and 4 and may last for weeks or months. Stage III, or the plateau or pseudo-stationary stage, usually begins between ages 2 and 10 and can last for years. Stage IV, or the late motor deterioration stage, can last for years or decades.
Rett syndrome is part of a spectrum of disorders with the same genetic cause. Other disorders on the spectrum include PPM-X syndrome, MECP2 duplication syndrome, and MECP2-related severe neonatal encephalopathy. These other conditions can affect males.
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Table of Contents:
1. Key Insights
2. Executive Summary of Rett Syndrome
3. Competitive Intelligence Analysis for Rett Syndrome
4. Rett Syndrome : Market Overview at a Glance
5. Rett Syndrome : Disease Background and Overview
6. Patient Journey
7. Rett Syndrome Epidemiology and Patient Population
8. Treatment Algorithm, Current Treatment, and Medical Practices
9. Unmet Needs
10. Key Endpoints of Rett Syndrome Treatment
11. Marketed Products
12. Emerging Therapies
13. Rett Syndrome : Seven Major Market Analysis
14. Attribute analysis
15. 7MM: Market Outlook
16. Access and Reimbursement Overview of Rett Syndrome
17. KOL Views
18. Market Drivers
19. Market Barriers
20. Appendix
21. DelveInsight Capabilities
22. Disclaimer
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